Ann Mainse was born in Fort Sam Houston, Texas, into a U.S. military family. She met her husband Ron in psychology class while attending Evangel University. Ann completed a Bachelor’s degree in Business Administration, and they were married in 1984. As a stay-at-home mom for 15 years, Ann often led a weekly women’s Bible study in her home. She began ministering on TV in 2001 as the writer and host of the daily devotional segment on 100 Huntley Street called “Sincerely Yours”, a two-year journey through the New Testament, which later became a book series. In 2005 Ann began hosting 100 Huntley Street alongside Ron, and in 2006 she launched a program with a women’s focus called Full Circle. Currently, besides periodic TV appearances, Ann speaks at women’s events, has a daily devotional radio segment on Joy 1250 AM, and a daily podcast called Sincerely Yours, featured on

Ann (and her husband, Ron) are the parents of three grown children and “Nana and Papa” to two precious grandchildren. They bring to Heart to Heart a passion for ministering to couples and families, and their vision is that every home would become a loving and unified haven, creating a legacy of hope for future generations.